magnolysin EC#: 3.4.24.62; ChemWhat Code: 1381057
| Product Name | magnolysin |
| Example Structure |  |
| Synonyms | Bovine neurosecretory granule protease cleaving pro-oxytocin/neurophysin, pro-ocytocin convertase, pro-ocytocin/neurophysin-converting enzyme, Pro-oxytocin convertase, Pro-oxytocin/neurophysin convertase, Proteinase, prooxyphysin |
| EC Number | 3.4.24.62 |
| CAS Registry Number | 110353-43-0;162875-09-4 |
| Comments | An endopeptidase of 58 kDa known from bovine pituitary neurosecretory granules and bovine and human corpus luteum [4,5]. Inhibited by EDTA [1]. |
| Cofactor | |
| History | |
| Reactions | Hydrolysis of polypeptides with Arg or Lys in P1 and P2, e.g. to hydrolyze pro-oxytocin at -Lys-Arg-|-Ala-Val-. The specificity further depends on the organization of a beta-turn-alpha-helix of nine or more residues containing the paired basic amino acids near the center. |
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