malate dehydrogenase [NAD(P)+] EC#: 1.1.1.299; ChemWhat Code: 1373404
| Product Name | malate dehydrogenase [NAD(P)+] |
| Example Structure | ![]() |
| Synonyms | MDH II |
| EC Number | 1.1.1.299 |
| CAS Registry Number | |
| Comments | This enzyme, which was characterized from the methanogenic archaeon Methanobacterium thermoautotrophicum, catalyses only the reduction of oxaloacetate, and can use NAD+ and NADP+ with similar specific activity [1]. Different from EC 1.1.1.37 (malate dehydrogenase (NAD+)), EC 1.1.1.82 (malate dehydrogenase (NADP+)) and EC 1.1.5.4 (malate dehydrogenase (quinone)). |
| Cofactor | |
| History | |
| Reactions | (S)-malate + NAD(P)(+) = oxaloacetate + NAD(P)H. |
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![Example Structure of malate dehydrogenase [NAD(P)+] EC#: 1.1.1.299](/wp-content/uploads/enzyme-structure/1.1.1.299.jpg)