malate synthase EC#: 2.3.3.9; ChemWhat Code: 1377206
| Product Name | malate synthase |
| Example Structure |  |
| Synonyms | EC 4.1.3.2, GCE, GCE(13-573), glcB, glyoxylate cycle enzyme, glyoxylate transacetase, glyoxylic transacetase, L-malate glyoxylate-lyase (CoA-acetylating), malate synthase, malate synthase 1, malate synthase A, malate synthase G, malate synthase H, malate synthetase, malic synthetase, malic-condensing enzyme, MLS, MSA, MSG, MSH, SSO1334 |
| EC Number | 2.3.3.9 |
| CAS Registry Number | 9013-48-3 |
| Comments | The enzyme catalyses the irreversible condensation of acetyl-CoA with glyoxylate to form (S)-malate. Among other functions, the enzyme participates in the glyoxylate cycle, a modified version of the TCA cycle that bypasses steps that lead to a loss of CO2. Formerly EC 4.1.3.2. |
| Cofactor | |
| History | |
| Reactions | Acetyl-CoA + H(2)O + glyoxylate = (S)-malate + CoA. |
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