maleylpyruvate hydrolase EC#: 3.7.1.23; ChemWhat Code: 1381806
| Product Name | maleylpyruvate hydrolase |
| Example Structure | ![]() |
| Synonyms | hbzF, maleylpyruvate hydrolase, maleylpyruvate hydrolase I, maleylpyruvate hydrolase II, Mph, MPH11 |
| EC Number | 3.7.1.23 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the bacterium?Pseudomonas alcaligenes?NCIMB 9867, catalyses the hydrolysis of 3-maleylpyruvate, the ring-cleavage product of gentisate. The enzyme can also act on a number of maleylpyruvate derivatives, such as (2E)-2-methyl-4,6-dioxohept-2-enedioate and (2E)-3-methyl-4,6-dioxohept-2-enedioate. Activated by Mn2+. May be identical to EC?3.7.1.5, acylpyruvate hydrolase. |
| Cofactor | Mn2+ |
| History | |
| Reactions | 3-maleylpyruvate + H(2)O = maleate + pyruvate. |
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