mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase EC#: 3.2.1.114; ChemWhat Code: 1380001
| Product Name | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase |
| Example Structure |  |
| Synonyms | 1,3(1,6)-alpha-D-mannosidase, 1,6-alpha-D-mannosidase, Afams1, alpha-1,3 mannosidase, alpha-1,3-mannosidase, alpha-D-mannosidase II, alpha-mannosidase, alpha-mannosidase II, alpha-mannosidase III, alpha-mannosidase IIx, alpha-MII, alpha1-3,6-mannosidase, Bt3991, class II alpha-D-mannosidase, class II alpha-mannosidase, class IIC alpha-mannosidase, dGMII, Drosophila GMII, exo-1,3-1,6-alpha-mannosidase, GH38 alpha-mannosidase II, GH38 enzyme, GH38 Golgi alpha-mannosidase II, GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase, glycoside hydrolase, GmII, Golgi alpha-mannosidase II, Golgi mannosidase IIx, human type II alpha-mannosidase, jack bean alpha-mannosidase, Man II, MAN IIx, MAN2A1, ManII, ManIII, mannose-trimming enzyme, mannosidase II, mannosidase, exo-1,3-1,6-alpha-, mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase II, MII, More, NAM, neutral alpha-mannosidase, SpGH38, TM1851 |
| EC Number | 3.2.1.114 |
| CAS Registry Number | |
| Comments | The enzyme, found in plants and animals, participates in the processing of?N-glycans in the Golgi apparatus. It removes two mannosyl residues, one linked by ¦Á1,3 linkage, and the other linked by ¦Á1,6 linkage, both of which are removed by the same catalytic site. The enzyme is sensitive to swainsonine. |
| Cofactor | |
| History | |
| Reactions | Hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3). |
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