mannosylfructose-phosphate synthase EC#: 2.4.1.246; ChemWhat Code: 1377556
| Product Name | mannosylfructose-phosphate synthase |
| Example Structure |  |
| Synonyms | MFPS |
| EC Number | 2.4.1.246 |
| CAS Registry Number | 92480-04-1 (not distinguished from EC 2.4.1.167) |
| Comments | This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg2+ or Mn2+ for activity. GDP-mannose can be replaced by ADP-mannose but with a concomitant decrease in activity. The product of this reaction is dephosphorylated by EC 3.1.3.79 (mannosylfructose-phosphate phosphatase) to form the non-reducing disaccharide mannosylfructose, which is the major endogenous osmolyte produced by several ¦Á-proteobacteria in response to osmotic stress. The F in the product name is used to indicate that the fructose residue of sucrose carries the substituent. |
| Cofactor | Mn2+ or Mg2+ |
| History | |
| Reactions | GDP-mannose + D-fructose 6-phosphate = Gdp + beta-D-fructofuranosyl- alpha-D-mannopyranoside 6(F)-phosphate. |
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