The enzyme catalyses the polymerization of ¦Â-D-mannuronate residues into a mannuronan polymer, an intermediate in the biosynthesis of alginate. It is found in brown algae and in alginate-producing bacterial species from the Pseudomonas and Azotobacter genera.
Cofactor
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GDP-alpha-D-mannuronate + ((1->4)-beta-D-mannuronosyl)(n) = Gdp + ((1->4)-beta-D-mannuronosyl)(n+1).