mannuronate-specific alginate lyase EC#: 4.2.2.3; ChemWhat Code: 1382497
| Product Name | mannuronate-specific alginate lyase |
| Example Structure |  |
| Synonyms | (poly alpha-l-guluronate) lyase, A1 alginate lyase, A1-II, A1-III, A1-IV’, A1m, A1mU, A9mC, A9mL, A9mT, AAlyase, AkAly30, AL2, alg, ALG-5, Alg-A, Alg17C, Alg2A, Alg7D, AlgA, AlgB, AlgE7, AlgI, alginase I, alginate lyase, alginate lyase A, alginate lyase A1-II, alginate lyase A1-II’, alginate lyase A1-III, alginate lyase AlyPEEC, alginate lyase Atu3025, alginate lyase B, alginate lyase C, alginate lyase I, alginate lyase VI, alginate lyase1-III, AlgL, ALY, ALY-1, Aly-SJ02, Aly1, Aly2, Aly28, Aly30, Aly32, Aly33, Aly35, Aly7B, AlyA, AlyA1, AlyA2, AlyA3, AlyA5, AlyB, AlyDW11, ALYIII, alyPEEC, AlyPI, AlyPM, AlyQ, AlyV5, AlyVI, Atu3025, AXE80_11190, CL2, EC 4.2.99.4, endo-type alginate lyase, endolytic poly(M) lyase, endolytic polymannuronate lyase, exotype alginate lyase, HdAlex, hdalex-1, HdAly, KJ-2 alginate lyase, LbAly28, lyase AlyA, lyase, alginate, Lysis protein, M block-specific polymannuronate lyase, mannuronate alginate lyase, MJ-3 alginate lyase, More, MY04_2544, NIS_0185, Oal17A, oligoalginate lyase, PL-5 alginate lyase, PM lyase, poly(1,4-beta-D-mannuronide) lyase, poly(beta-D-1,4-mannuronide) lyase, Poly(beta-D-mannuronate) lyase, poly(M) lyase, poly(M)lyase, Poly(mana) alginate lyase, poly(mana)alginate lyase, polymannuronate lyase, polyMG-specific alginate lyase, protein PA1167, SP2, V12B01_24254, V12B01_24259, WP_053404615 |
| EC Number | 4.2.2.3 |
| CAS Registry Number | 86922-62-5 |
| Comments | The enzyme catalyses the degradation of alginate by a ¦Â-elimination reaction. It cleaves the (1¡ú4) bond between ¦Â-D-mannuronate and either ¦Á-L-guluronate or ¦Â-D-mannuronate, generating oligosaccharides with 4-deoxy-¦Á-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and ¦Â-D-mannuronate at the reducing end. Depending on the composition of the substrate, the enzyme produces oligosaccharides ranging from two to four residues, with preference for shorter products.?cf. EC?4.2.2.11, guluronate-specific alginate lyase. |
| Cofactor | |
| History | |
| Reactions | Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy- alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and beta-D-mannuronate at their reducing end. |
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