(+)-menthofuran synthase EC#: 1.14.14.143; ChemWhat Code: 1375651

Product Name (+)-menthofuran synthase
Example Structure Example Structure of (+)-menthofuran synthase EC#: 1.14.14.143
Synonyms (+)-MFS, (+)-pulegone-9-hydroxylase, menthofuran synthase, MFS
EC Number 1.14.14.143
CAS Registry Number
Comments A cytochrome P450 (heme-thiolate) protein. The conversion of substrate into product involves the hydroxylation of the syn-methyl (C9), intramolecular cyclization to the hemiketal and dehydration to the furan [1]. This is the second cytochrome P450-mediated step of monoterpene metabolism in peppermint, with the other step being catalysed by EC 1.14.14.99, (S)-limonene 3-monooxygenase [1].
Cofactor heme-thiolate
History
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