meromycolic acid enoyl-[acyl-carrier-protein] reductase EC#: 1.3.1.118; ChemWhat Code: 1374097
| Product Name | meromycolic acid enoyl-[acyl-carrier-protein] reductase |
| Example Structure | ![Example Structure of meromycolic acid enoyl-[acyl-carrier-protein] reductase EC#: 1.3.1.118](/wp-content/uploads/enzyme-structure/1.3.1.118.jpg) |
| Synonyms | 2-trans-enoyl-ACP reductase, 2-trans-enoyl-ACP(CoA) reductase, 2-trans-enoyl-acyl carrier protein reductase, enoyl acyl carrier protein reductase, enoyl acyl carrier protein reductase InhA, enoyl-ACP reductase, enoyl-ACP reductase InhA, enoyl-acyl carrier protein reductase, FAS-II enoyl reductase, FASII enoyl-ACP reductase, InhA, InhA Protein, MtInhA |
| EC Number | 1.3.1.118 |
| CAS Registry Number | |
| Comments | InhA is a component of the fatty acid synthase (FAS) II system of Mycobacterium tuberculosis, catalysing an enoyl-[acyl-carrier-protein] reductase step. The enzyme acts on very long and unsaturated fatty acids that form the meromycolic component of mycolic acids. It extends FASI-derived C20 fatty acids to form C60 to C90 mycolic acids. The enzyme, which forms a homotetramer, is the target of the preferred antitubercular drug isoniazid. |
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