methylmalonate-semialdehyde dehydrogenase (CoA-acylating) EC#: 1.2.1.27; ChemWhat Code: 1373769
| Product Name | methylmalonate-semialdehyde dehydrogenase (CoA-acylating) |
| Example Structure |  |
| Synonyms | Aldh6a1, dddC, FG99_15390, KES23460, malonate-semialdehyde dehydrogenase, methylmalonate semialdehyde dehydrogenase, methylmalonate semialdehyde dehydrogenase protein, methylmalonate-semialdehyde dehydrogenase, methylmalonic acid semialdehyde dehydrogenase, MMSADH, MMSDH, MSDH, NAD-dependent malonate-semialdehyde dehydrogenase, OdoMMSDH, OsALDH6, PA3570, SSO1218 |
| EC Number | 1.2.1.27 |
| CAS Registry Number | 37205-49-5 |
| Comments | Also converts 3-oxopropanoate into acetyl-CoA [3]. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding [3]. Bicarbonate rather than CO2 is released as a final product [3]. |
| Cofactor | |
| History | |
| Reactions | 2-methyl-3-oxopropanoate + CoA + H(2)O + NAD(+) = propanoyl-CoA + HCO(3)(-) + Nadh. |
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