| Product Name |
molybdopterin synthase sulfurtransferase |
| Example Structure |
 |
| Synonyms |
CnxF protein, IscS, L-cysteine desulfurase, MOCS3, MOCS3 rhodanese-like domain, MOCS3-RLD, MoeB, molybdenum cofactor biosynthesis protein, molybdenum cofactor synthesis protein 3, molybdopterin synthase sulfurase, molybdopterin synthase sulfurylase |
| EC Number |
2.8.1.11 |
| CAS Registry Number |
|
| Comments |
The enzyme transfers sulfur to form a thiocarboxylate moiety on the C-terminal glycine of the small subunit of EC?2.8.1.12, molybdopterin synthase. In the human, the reaction is catalysed by the rhodanese-like C-terminal domain (cf. EC?2.8.1.1) of the MOCS3 protein, a bifunctional protein that also contains EC?2.7.7.80, molybdopterin-synthase adenylyltransferase, at the N-terminal domain. |
| Cofactor |
|
| History |
|
| Reactions |
[Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine + reduced acceptor = Amp + [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + [cysteine desulfurase] + oxidized acceptor. |
