morphine 6-dehydrogenase EC#: 1.1.1.218; ChemWhat Code: 1373295
Product Name | morphine 6-dehydrogenase |
Example Structure | |
Synonyms | AKR1C34, M6DH, More, morphine 6-dehydrogenase, morphine-6-dehydrogenase, naloxone reductase |
EC Number | 1.1.1.218 |
CAS Registry Number | 106640-77-1;97002-71-6 |
Comments | Also acts on some other alkaloids, including codeine, normorphine and ethylmorphine, but only very slowly on 7,8-saturated derivatives such as dihydromorphine and dihydrocodeine. In the reverse direction, also reduces naloxone to the 6¦Á-hydroxy analogue. Activated by 2-mercaptoethanol. |
Cofactor | |
History | |
Reactions | Morphine + NAD(P)(+) = morphinone + NAD(P)H. |
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