| Product Name |
morphine 6-dehydrogenase |
| Example Structure |
 |
| Synonyms |
AKR1C34, M6DH, More, morphine 6-dehydrogenase, morphine-6-dehydrogenase, naloxone reductase |
| EC Number |
1.1.1.218 |
| CAS Registry Number |
106640-77-1;97002-71-6 |
| Comments |
Also acts on some other alkaloids, including codeine, normorphine and ethylmorphine, but only very slowly on 7,8-saturated derivatives such as dihydromorphine and dihydrocodeine. In the reverse direction, also reduces naloxone to the 6¦Á-hydroxy analogue. Activated by 2-mercaptoethanol. |
| Cofactor |
|
| History |
|
| Reactions |
Morphine + NAD(P)(+) = morphinone + NAD(P)H. |
