mRNA N1-methyladenine demethylase EC#: 1.14.11.54; ChemWhat Code: 1375147
Product Name | mRNA N1-methyladenine demethylase |
Example Structure | |
Synonyms | ABH3, AlkB, ALKBH3, alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, PCA-1, prostate cancer antigen-1 |
EC Number | 1.14.11.54 |
CAS Registry Number | |
Comments | Contains iron(II). Catalyses oxidative demethylation of mRNA N1-methyladenine. The enzyme is also involved in alkylation repair in DNA [2]. |
Cofactor | Fe2+ |
History | |
Reactions | N(1)-methyladenine in mRNA + 2-oxoglutarate + O(2) = adenine in mRNA + formaldehyde + succinate + CO(2). |
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