mRNA N1-methyladenine demethylase EC#: 1.14.11.54; ChemWhat Code: 1375147
| Product Name | mRNA N1-methyladenine demethylase |
| Example Structure | ![]() |
| Synonyms | ABH3, AlkB, ALKBH3, alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, PCA-1, prostate cancer antigen-1 |
| EC Number | 1.14.11.54 |
| CAS Registry Number | |
| Comments | Contains iron(II). Catalyses oxidative demethylation of mRNA N1-methyladenine. The enzyme is also involved in alkylation repair in DNA [2]. |
| Cofactor | Fe2+ |
| History | |
| Reactions | N(1)-methyladenine in mRNA + 2-oxoglutarate + O(2) = adenine in mRNA + formaldehyde + succinate + CO(2). |
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