mRNA(cytosine6666) deaminase EC#: 3.5.4.36; ChemWhat Code: 1381483

Product Name mRNA(cytosine6666) deaminase
Example Structure Example Structure of mRNA(cytosine6666) deaminase EC#: 3.5.4.36
Synonyms apo B messenger RNA editing protein, apoB mRNA-editing enzyme catalytic polypeptide 1, APOBEC-1, APOBEC1, apolipoprotein B mRNA editing enzyme, apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1, REPR
EC Number 3.5.4.36
CAS Registry Number
Comments The apolipoprotein B mRNA editing enzyme complex catalyses the editing of apolipoprotein B mRNA at cytidine6666?to uridine, thereby transforming the codon for glutamine-2153 to a termination codon. Editing results in translation of a truncated apolipoprotein B isoform (apoB-48) with distinct functions in lipid transport. The catalytic component (APOBEC-1) contains zinc at the active site [3].
Cofactor
History
Reactions Cytosine(6666) in apolipoprotein B mRNA + H(2)O = uracil(6666) in apolipoprotein B mRNA + NH(3).

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