Muramoyltetrapeptide carboxypeptidase EC#: 3.4.17.13; ChemWhat Code: 1380397

Product Name Muramoyltetrapeptide carboxypeptidase
Example Structure Example Structure of Muramoyltetrapeptide carboxypeptidase EC#: 3.4.17.13
Synonyms Carboxypeptidase II, Carboxypeptidase IIW, Carboxypeptidase, lysyl-D-alanine, Carboxypeptidase, muramoyltetrapeptide, cjj81176_0915, DacB, L,D-carboxypeptidase A, L-Lysyl-D-alanine carboxypeptidase, LD-Carboxypeptidase, LdcA, LdcA1, LdcA2, LdcB, muramoyltetrapeptide carboxypeptidase, peptidase U61, Pgp2, Spr0554
EC Number 3.4.17.13
CAS Registry Number 60063-80-1
Comments Variants are known from various microorganisms. Involved in peptidoglycan synthesis, catalysing both decarboxylation and transpeptidation. Stimulated by divalent cations such as Mg2+?and Ca2+, but not by Zn2+. Inhibited by thiol-blocking reagents, but unaffected by penicillin.
Cofactor
History
Reactions GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + H(2)O = GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + D-alanine.

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