The enzyme is highly specific for GalNAc as substrate, but has slight activity with?D-galactose [2]. Requires Mg2+, Mn2+?or Co2+?for activity, with Mg2+?resulting in by far the greatest stimulation of enzyme activity.
Cofactor
Mg2+
History
Reactions
Atp + N-acetyl-alpha-D-galactosamine = adp + N-acetyl-alpha-D- galactosamine 1-phosphate.