N-acetylgalactosaminide beta-1,3-galactosyltransferase EC#: 2.4.1.122; ChemWhat Code: 1377407
| Product Name | N-acetylgalactosaminide beta-1,3-galactosyltransferase |
| Example Structure |  |
| Synonyms | 3betaGal-T4, beta-galactosyltransferase, C1beta3GalT, C1GalT, C1GALT1, C1GalTA, Ce-T-synthase, core 1 beta1,3-galactosyltransferase, core 1 beta3-Gal-T, core 1 beta3-Gal-transferase, core 1 galactosyltransferase A, core 1 GalT, core 1 synthase, core 1 transferase, core 1 UDP-alpha-galactose (UDP-Gal):GalNAca1-Ser/Thr beta1,3-galactosyltransferase, core-1 beta3GalT, dC1beta3GalT1, galactosyltransferase, galactosyltransferase, uridine diphosphogalactose-mucin beta-(1-3)-, mucin-type core-1 beta1-3 galactosyltransferase, O-glycan core 1 UDPgalactose:N-acetyl-alpha-galactosaminyl-R beta3-galactosyltransferase, T-synthase, UDP-Gal:GalNAc-alpha-Ser/Thr beta3-galactosyltransferase, UDP-Gal:glycoprotein-alpha-GalNAc beta3 galactosyltransferase, UDP-Gal:N-acetylgalactosaminide mucin:beta1,3-galactosyltransferase, UDP-galactose:glycoprotein-alpha-GalNAc beta3-galactosyltransferase, uridine diphosphogalactose-mucin beta-(1-3)-galactosyltransferase, WbnJ |
| EC Number | 2.4.1.122 |
| CAS Registry Number | 97089-61-7 |
| Comments | The eukaryotic enzyme can act on non-reducing O-serine-linked N-acetylgalactosamine residues in mucin glycoproteins, forming the T-antigen. The bacterial enzyme, found in some pathogenic strains, is involved in biosynthesis of the O-antigen repeating unit. Formerly EC 2.4.1.307. |
| Cofactor | |
| History | |
| Reactions | UDP-alpha-D-galactose + N-acetyl-alpha-D-galactosaminyl-R = Udp + beta-D- galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R. |
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