N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase EC#: 2.4.1.289; ChemWhat Code: 1377621

Product Name N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase
Example Structure Example Structure of N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase EC#: 2.4.1.289
Synonyms cell wall rhamnosyltransferase, Cj1125c, dTDP-Rha:alpha-D-GlcNAc-pyrophosphate polyprenol, alpha-3-L-rhamnosyltransferase, lmo1080, PglA, RmlT, WbbL
EC Number 2.4.1.289
CAS Registry Number
Comments Requires Mn2+ or Mg2+. Isolated from Mycobacterium smegmatis [1] and Mycobacterium tuberculosis [2]. The enzyme catalyses the addition of a rhamnosyl unit to N-acetyl-¦Á-D-glucosaminyl-diphospho-trans,octacis-decaprenol, completing the synthesis of the linkage unit that attaches the arabinogalactan moiety to the peptidoglycan moiety in Mycobacterial cell wall.
Cofactor Mn2+ or Mg2+
History
Reactions dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho- trans,octacis-decaprenol = dTDP + alpha-L-rhamnopyranosyl-(1->3)-N- acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol.

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