N-acetylglucosaminylphosphatidylinositol deacetylase EC#: 3.5.1.89; ChemWhat Code: 1381291
| Product Name | N-acetylglucosaminylphosphatidylinositol deacetylase |
| Example Structure | ![]() |
| Synonyms | 2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1->6)-phosphatidylinositol de-N-acetylase, Acetylglucosaminylphosphatidylinositol deacetylase, alpha-D-GlcpNAc-PI de-N-acetylase, Deacetylase, acetylglucosaminylphosphatidylinositol, deNAc, EC 3.1.1.69, GlcNAc-phosphatidylinositol deacetylase, GlcNAc-PI de-N-acetylase, GlcNAc-PI deacetylase, GlcNAc-PI-de-N-acetylase, GlcNAc-PI-deacetylase, GPI, N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, N-acetylglucosamine-phosphatidylinositolde-N-acetylase, N-acetylglucosaminyl phosphatidylinositol de-N-acetylase, N-Acetylglucosaminylphosphatidylinositol de-N-acetylase, N-acetylglucosaminylphosphatidylinositol deacetylase, PIG-L, PIG-L protein, TbGPI12 |
| EC Number | 3.5.1.89 |
| CAS Registry Number | |
| Comments | Involved in the second step of glycosylphosphatidylinositol (GPI) anchor formation in all eukaryotes. The enzyme appears to be composed of a single subunit (PIG-L in mammalian cells and GPI12 in yeast). In some species, the long-chain?sn-1-acyl group of the phosphatidyl group is replaced by a long-chain alkyl or alk-1-enyl group. |
| Cofactor | |
| History | |
| Reactions | 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O = 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate. |
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