N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase EC#: 2.4.1.150; ChemWhat Code: 1377440
| Product Name | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase |
| Example Structure |  |
| Synonyms | acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-acetyllactosaminide beta1–>6-, beta1-6GnT, C2GnT2, dIHnT, distally acting I-branching beta1,6-N-acetylglucosaminyltransferase, Galbeta1–>4GlcNAc-R beta1–>6 N-acetylglucosaminyltransferase, GCNT2, Gcnt2 gene product, gcnt3, I beta1,6-N-acetylglucosaminyltransferase, I N-acetylglucosaminyltransferase, I-branching beta-1,6-N-acetylglucosaminyltransferase, IGnT, More, N-acetylglucosaminyltransferase, N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferase, UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminide 6-beta-N-acetyl-D-glucosaminyltransferase, uridine diphosphoacetylglucosamine-acetyllactosaminide beta1–>6-acetylglucosaminyltransferase |
| EC Number | 2.4.1.150 |
| CAS Registry Number | 85638-40-0 |
| Comments | The enzyme acts on poly-N-acetyllactosamine [glycan chains of ¦Â-D-galactosyl-(1¡ú4)-N-acetyl-D-glucosamine units connected by ¦Â(1,3) linkages] attached to proteins or lipids. It transfers a GlcNAc residue by ¦Â(1,6) linkage to galactosyl residues close to non-reducing terminals, introducing a branching pattern known as I branching. |
| Cofactor | |
| History | |
| Reactions | UDP-N-acetyl-alpha-D-glucosamine + beta-D-Gal-(1->4)-beta-D-GlcNAc- (1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-R = Udp + beta-D-Gal-(1->4)-beta- D-GlcNAc-(1->3)-(beta-D-GlcNAc-(1->6))-beta-D-Gal-(1->4)-beta-D-GlcNAc-R. |
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