N-acetylphosphatidylethanolamine-hydrolysing phospholipase D EC#: 3.1.4.54; ChemWhat Code: 1379633

Product Name N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
Example Structure Example Structure of N-acetylphosphatidylethanolamine-hydrolysing phospholipase D EC#: 3.1.4.54
Synonyms anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, N-acyl-phosphatidylethanolamine-specific phospholipase D, N-acylphosphatidylethanolamine-specific phospholipase D, NAPE-hydrolysing phospholipase D, NAPE-PLD, NAPEPLD
EC Number 3.1.4.54
CAS Registry Number
Comments This enzyme is involved in the biosynthesis of anandamide. It does not hydrolyse phosphatidylcholine and phosphatidylethanolamine [1]. No transphosphatidation [1]. The enzyme contains Zn2+?and is activated by Mg2+?or Ca2+?[2].
Cofactor Zn2+
History
Reactions An N-acylphosphatidylethanolamine + H(2)O = an N-acylethanolamine + a 1,2-diacylglycerol 3-phosphate.

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