| Product Name |
N-carbamoyl-D-amino-acid hydrolase |
| Example Structure |
 |
| Synonyms |
Amidase, N-carbamoyl-D-amino acid, carbamoylase, D-N-alpha-Carbamoylase, D-NCAase, Dcase, DCase-M3, DCHase, N-carbamoyl D-amino acid amidohydrolase, N-Carbamoyl-D-amino acid amidase, N-carbamoyl-D-amino acid amidohydrolase, N-Carbamyl amino acid amidohydrolase, N-Carbamyl-D-amino acid amidohydrolase |
| EC Number |
3.5.1.77 |
| CAS Registry Number |
71768-08-6 |
| Comments |
This enzyme, along with EC?3.5.1.87?(N-carbamoyl-L-amino-acid hydrolase), EC?5.1.99.5?(hydantoin racemase) and hydantoinase, forms part of the reaction cascade known as the “hydantoinase process”, which allows the total conversion of?D,L-5-monosubstituted hydantoins into optically pure?D- or?L-amino acids [2]. It has strict stereospecificity for?N-carbamoyl-D-amino acids and does not act upon the corresponding?L-amino acids or?N-formyl amino acids,?N-carbamoyl-sarcosine, -citrulline, -allantoin and -ureidopropionate, which are substrates for other amidohydrolases. |
| Cofactor |
|
| History |
|
| Reactions |
N-carbamoyl-D-amino acid + H(2)O = D-amino acid + NH(3) + CO(2). |
