N-succinylarginine dihydrolase EC#: 3.5.3.23; ChemWhat Code: 1381418
| Product Name | N-succinylarginine dihydrolase |
| Example Structure |  |
| Synonyms | AruB, AstB, SADH |
| EC Number | 3.5.3.23 |
| CAS Registry Number | |
| Comments | Arginine,?N2-acetylarginine and?N2-glutamylarginine do not act as substrates [3]. This is the second enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine [1]. This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. The five enzymes involved in this pathway are EC?2.3.1.109?(arginine?N-succinyltransferase), EC?3.5.3.23?(N-succinylarginine dihydrolase), EC?2.6.1.81?(succinylornithine transaminase), EC?1.2.1.71?(succinylglutamate semialdehyde dehydrogenase) and EC?3.5.1.96?(succinylglutamate desuccinylase). |
| Cofactor | |
| History | |
| Reactions | N(2)-succinyl-L-arginine + 2 H(2)O = N(2)-succinyl-L-ornithine + 2 NH(3) + CO(2). |
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