N4-bis(aminopropyl)spermidine synthase EC#: 2.5.1.128; ChemWhat Code: 1378072
| Product Name | N4-bis(aminopropyl)spermidine synthase |
| Example Structure |  |
| Synonyms | BpsA, TK1691 |
| EC Number | 2.5.1.128 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the thermophilic archaeon Thermococcus kodakarensis, synthesizes the branched-chain polyamine N4-bis(aminopropyl)spermidine, which is required for cell growth at high-temperature. When spermine is used as substrate, the enzyme forms N4-aminopropylspermine. |
| Cofactor | |
| History | |
| Reactions | 2 S-adenosyl 3-(methylthio)propylamine + spermidine = 2 S-methyl- 5′-thioadenosine + N(4)-bis(aminopropyl)spermidine. |
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