NADPH dehydrogenase (quinone) EC#: 1.6.5.10; ChemWhat Code: 1374550
| Product Name | NADPH dehydrogenase (quinone) |
| Example Structure |  |
| Synonyms | AKR1C9, ArsH, azoreductase, CBR4, dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate (quinone), MdaB, More, NADPH oxidase, NADPH quinone oxidoreductase, NADPH quinone oxidoreductase 1, NADPH quinone reductase, NADPH-dependent quinone reductase, NADPH-quinone oxidoreductase, NADPH:quinone oxidoreductase 1, NQO1, PpAzoR, Zta1p |
| EC Number | 1.6.5.10 |
| CAS Registry Number | 37256-37-4 |
| Comments | A flavoprotein [1,2]. The enzyme from Escherichia coli is specific for NADPH and is most active with quinone derivatives and ferricyanide as electron acceptors [3]. Menaquinone can act as acceptor. The enzyme from hog liver is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol [1]. |
| Cofactor | flavoprotein |
| History | |
| Reactions | Nadph + a quinone = NADP(+) + a quinol. |
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