naphthalene 1,2-dioxygenase EC#: 1.14.12.12; ChemWhat Code: 1375181

Product Name naphthalene 1,2-dioxygenase
Example Structure Example Structure of naphthalene 1,2-dioxygenase EC#: 1.14.12.12
Synonyms NAG, NAHA, nahAc, naphthalene 1,2-dioxygenase, naphthalene dioxygenase, naphthalene oxygenase, NDO, oxygenase, naphthalene di-
EC Number 1.14.12.12
CAS Registry Number 9074/4/8
Comments This enzyme is a member of the ring-hydroxylating dioxygenase (RHD) family of bacterial enzymes that play a critical role in the degradation of aromatic compounds, such as polycyclic aromatic hydrocarbons [5]. This enzyme comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.3, ferredoxin¡ªNAD+ reductase), an iron-sulfur oxygenase, and ferredoxin. Requires Fe2+.
Cofactor Fe cation
History
Reactions Naphthalene + Nadh + O(2) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+).

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