neamine phosphoribosyltransferase EC#: 2.4.2.49; ChemWhat Code: 1377810
| Product Name | neamine phosphoribosyltransferase |
| Example Structure |  |
| Synonyms | btrL, neoM |
| EC Number | 2.4.2.49 |
| CAS Registry Number | |
| Comments | Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin. The enzyme requires a divalent metal ion, optimally Mg2+, Ni2+ or Co2+. |
| Cofactor | divalent metal cation |
| History | |
| Reactions | Neamine + 5-phospho-alpha-D-ribose 1-diphosphate = 5”-phosphoribostamycin + diphosphate. |
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