neomycin C transaminase EC#: 2.6.1.95; ChemWhat Code: 1378253
| Product Name | neomycin C transaminase |
| Example Structure |  |
| Synonyms | 6′-oxoglucosaminyl:L-glutamate aminotransferase, Neo-18, neoB, neoN |
| EC Number | 2.6.1.95 |
| CAS Registry Number | |
| Comments | The reaction occurs?in vivo?in the opposite direction. Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. Works in combination with EC?1.1.3.44, 6”’-hydroxyneomycin C oxidase, to replace the 6”’-hydroxy group of 6”’-deamino-6”’-hydroxyneomycin C with an amino group. The enzyme, characterized from the bacterium?Streptomyces fradiae, can also catalyse EC?2.6.1.93, neamine transaminase. |
| Cofactor | |
| History | |
| Reactions | Neomycin C + 2-oxoglutarate = 6”’-deamino-6”’-oxoneomycin c + L-glutamate. |
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