nephthenol synthase EC#: 4.2.3.149; ChemWhat Code: 1382742
| Product Name | nephthenol synthase |
| Example Structure |  |
| Synonyms | DtcycA, DtcycB |
| EC Number | 4.2.3.149 |
| CAS Registry Number | |
| Comments | Requires Mg2+. Two isozymes with this activity were isolated from the bacterium?Streptomyces?sp. SANK 60404. The enzyme encoded by the DtcycA gene also produces cembrene C (see?4.2.3.148, cembrene C synthase), while the enzyme encoded by the DtcycB gene also produces (R)-cembrene A and (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol (see EC?4.2.3.150, cembrene A synthase, and EC?4.2.3.151, pentamethylcyclopentadecatrienol synthase). |
| Cofactor | Mg2+ |
| History | |
| Reactions | Geranylgeranyl diphosphate + H(2)O = (R)-nephthenol + diphosphate |
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