neutrophil collagenase EC#: 3.4.24.34; ChemWhat Code: 1381010
| Product Name | neutrophil collagenase |
| Example Structure |  |
| Synonyms | collagenase-2, collagenases-8, EC 3.4.24.7, HNC, human neutrophil collagenase, matrix metalloproteinase, Matrix metalloproteinase 8, Matrix metalloproteinase-8, metalloproteinase-8, MetMMP-8, MMP-7, MMP-8, MMP8, neutrophil collagenase, neutrophil collagenase MMP-8, neutrophil interstitial collagenase, PheMMP-8, PMNL collagenase, PMNL-CL, polymorphonuclear leukocyte collagenase, whMMP-8 |
| EC Number | 3.4.24.34 |
| CAS Registry Number | 9001/12/1 |
| Comments | Similar to interstitial collagenase in specificity, but the product of a different gene and highly glycosylated. Stored in the specific granules of neutrophil leukocytes. In peptidase family?M10?(interstitial collagenase family). Formerly included in EC?3.4.24.7. |
| Cofactor | Zn2+;Ca2+ |
| History | |
| Reactions | Cleavage of interstitial collagens in the triple helical domain. Unlike Ec 3.4.24.7, this enzyme cleaves type Iii collagen more slowly than type I. |
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