nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase EC#: 2.4.2.21; ChemWhat Code: 1377763
| Product Name | nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase |
| Example Structure |  |
| Synonyms | 5,6-dimethylbenzimidazole phosphoribosyltransferase, ArsAB, CobT, CobT2, N(1)-alpha-phosphoribosyltransferase, N1-alpha-phosphoribosyltransferase, nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase, nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase, NN:DBI PRT, phosphoribosyltransferase, nicotinate mononucleotide-dimethylbenzimidazole, SoArsAB |
| EC Number | 2.4.2.21 |
| CAS Registry Number | 37277-76-2 |
| Comments | Also acts on benzimidazole, and the clostridial enzyme acts on adenine to form 7-¦Á-D-ribosyladenine 5′-phosphate. The product of the reaction, ¦Á-ribazole 5′-phosphate, forms part of the corrin-biosynthesis pathway and is a substrate for EC 2.7.8.26, adenosylcobinamide-GDP ribazoletransferase [4]. It can also be dephosphorylated to form ¦Á-ribazole by the action of EC 3.1.3.73, ¦Á-ribazole phosphatase. |
| Cofactor | |
| History | |
| Reactions | Beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole = nicotinate + alpha-ribazole 5′-phosphate. |
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