nicotine dehydrogenase EC#: 1.5.99.4; ChemWhat Code: 1374490
| Product Name | nicotine dehydrogenase |
| Example Structure | ![]() |
| Synonyms | 6-hydroxy-D-nicotine oxidase, 6-hydroxy-L-nicotine oxidase, D-nicotine oxidase, NctA, NDH, NdhAB, nicotine dehydrogenase, nicotine oxidase, nicotinic acid hydroxylase |
| EC Number | 1.5.99.4 |
| CAS Registry Number | 37256-31-8 |
| Comments | A metalloprotein (FMN). The enzyme can act on both the naturally found (S)-enantiomer and the synthetic (R)-enantiomer of nicotine, with retention of configuration in both cases [4]. |
| Cofactor | FMN |
| History | |
| Reactions | Nicotine + acceptor + H(2)O = (S)-6-hydroxynicotine + reduced acceptor. |
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