nitric-oxide synthase (flavodoxin) EC#: 1.14.14.47; ChemWhat Code: 1375555

Product Name nitric-oxide synthase (flavodoxin)
Example Structure Example Structure of nitric-oxide synthase (flavodoxin) EC#: 1.14.14.47
Synonyms bNOS, GK1676, nitric oxide synthetase, NO synthase, NOS, SANOS, YumC
EC Number 1.14.14.47
CAS Registry Number
Comments Binds heme (iron protoporphyrin IX) and tetrahydrobiopterin. The enzyme, found in bacteria and archaea, consist of only an oxygenase domain and functions together with bacterial ferredoxins or flavodoxins. The orthologous enzymes from plants and animals also contain a reductase domain and use only NADPH as the electron donor (cf. EC 1.14.13.39).
Cofactor ferriheme b;5,6,7,8-tetrahydrobiopterin
History
Reactions 2 L-arginine + 3 reduced flavodoxin + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H(2)O.

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