| Product Name |
O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase |
| Example Structure |
 |
| Synonyms |
MMPSepSecS, O-phosphoserine tRNA: selenocysteine synthase, O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase, SelA, Selenocysteinyl-tRNA synthase, Sep tRNA: Sec synthase, SepSecS, SLA/LP |
| EC Number |
2.9.1.2 |
| CAS Registry Number |
|
| Comments |
A pyridoxal-phosphate protein [4]. In archaea and eukarya selenocysteine formation is achieved by a two-step process: EC?2.7.1.164?(O-phosphoseryl-tRNASec?kinase) phosphorylates the endogenous?L-seryl-tRNASec?to?O-phospho-L-seryl-tRNASec, and then this misacylated amino acid-tRNA species is converted to?L-selenocysteinyl-tRNASec?by Sep-tRNA:Sec-tRNA synthase. |
| Cofactor |
pyridoxal 5′-phosphate |
| History |
|
| Reactions |
O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H(2)O = L-selenocysteinyl-tRNA(Sec) + 2 phosphate. |
