oligopeptidase A EC#: 3.4.24.70; ChemWhat Code: 1381071
Product Name
oligopeptidase A
Example Structure
Synonyms
68000-M Signalpeptide hydrolase, More, oligopeptidase A, OpdA, TOP, Top1, Top2
EC Number
3.4.24.70
CAS Registry Number
148266-37-9
Comments
Known from?Escherichia coli?and?Salmonella typhimurium. A zinc metallopeptidase, in peptidase family?M3?(thimet oligopeptidase family), but differs from thimet oligopeptidase in lack of thiol-activation.
Cofactor
Zn2+
History
Reactions
Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1′ residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).
