pantetheine hydrolase EC#: 3.5.1.92; ChemWhat Code: 1381294
| Product Name | pantetheine hydrolase |
| Example Structure |  |
| Synonyms | GPI-80, PAGEL, pantetheinase, pantetheinase-associated gene expressed in leukocytes, pantetheinases, pantetheine hydrolase, vanin, vanin 1, vanin gene family, vanin-1, vanin-2, vanin-3, VNN-1, VNN1, VNN2, VNN3 |
| EC Number | 3.5.1.92 |
| CAS Registry Number | |
| Comments | The enzyme hydrolyses only one of the amide bonds of pantetheine. The substrate analogues phosphopantetheine and CoA are not substrates. The enzyme recycles pantothenate (vitamin B5) and produces cysteamine, a potent anti-oxidant [5]. |
| Cofactor | |
| History | |
| Reactions | (R)-pantetheine + H(2)O = (R)-pantothenate + 2-aminoethanethiol. |
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