pantoate kinase EC#: 2.7.1.169; ChemWhat Code: 1378557
| Product Name | pantoate kinase |
| Example Structure |  |
| Synonyms | COG1829, Mhun_0831, PoK, TK2141, TK2141 protein |
| EC Number | 2.7.1.169 |
| CAS Registry Number | |
| Comments | The conversion of (R)-pantoate to (R)-4′-phosphopantothenate is part of the pathway leading to biosynthesis of 4′-phosphopantetheine, an essential cofactor of coenzyme A and acyl-carrier protein. In bacteria and eukaryotes this conversion is performed by condensation with ¦Â-alanine, followed by phosphorylation (EC?6.3.2.1?and EC?2.7.1.33, respectively). In archaea the order of these two steps is reversed, and phosphorylation precedes condensation with ¦Â-alanine. |
| Cofactor | |
| History | |
| Reactions | Atp + (R)-pantoate = adp + (R)-4-phosphopantoate. |
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