papain EC#: 3.4.22.2; ChemWhat Code: 1380677
| Product Name | papain |
| Example Structure | ![]() |
| Synonyms | Adolph’s Meat Tenderizer, arbuz, EC 3.4.4.10, enzeco papain, papain, papain-like cysteine protease, papain-like protease, papaine, papaya peptidase I, papaya proteinase 1, papayotin, PLCP, PLpro, PPI, summetrin, velardon |
| EC Number | 3.4.22.2 |
| CAS Registry Number | 9001-73-4 |
| Comments | Type example of peptidase family?C1?from latex of the papaya (Carica papaya) fruit. Inhibited by compound E-64 and proteins of the cystatin family. Formerly EC?3.4.4.10. |
| Cofactor | |
| History | |
| Reactions | Hydrolysis of proteins with broad specificity for peptide bonds, but preference for an amino acid bearing a large hydrophobic side chain at the P2 position. Does not accept Val in P1′. |
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