paromamine 6′-oxidase EC#: 1.1.3.43; ChemWhat Code: 1373621
| Product Name | paromamine 6′-oxidase |
| Example Structure |  |
| Synonyms | btrQ, neoG, neoQ, tacB |
| EC Number | 1.1.3.43 |
| CAS Registry Number | |
| Comments | Contains FAD. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Works in combination with EC 2.6.1.93, neamine transaminase, to replace the 6-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 1.1.3.44, 6”’-hydroxyneomycin C oxidase. |
| Cofactor | FAD |
| History | |
| Reactions | Paromamine + O(2) = 6′-dehydroparomamine + H(2)O(2). |
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