paromamine 6′-oxidase EC#: 1.1.3.43; ChemWhat Code: 1373622

Product Name paromamine 6′-oxidase
Example Structure Example Structure of paromamine 6'-oxidase EC#: 1.1.3.43
Synonyms btrQ, neoG, neoQ, tacB
EC Number 1.1.3.43
CAS Registry Number
Comments Contains FAD. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Works in combination with EC 2.6.1.93, neamine transaminase, to replace the 6-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 1.1.3.44, 6”’-hydroxyneomycin C oxidase.
Cofactor FAD
History
Reactions Paromamine + O(2) = 6′-dehydroparomamine + H(2)O(2).

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