peptide-aspartate beta-dioxygenase EC#: 1.14.11.16; ChemWhat Code: 1375090
| Product Name | peptide-aspartate beta-dioxygenase |
| Example Structure |  |
| Synonyms | AAH, asparaginyl hydroxylase factor inhibiting HIF-1, aspartate beta-hydroxylase, aspartate-beta-hydroxylase, aspartyl (asparaginyl) beta-hydroxylase, aspartyl (asparaginyl)-beta-hydroxylase, aspartyl beta-hydroxylase, aspartyl-(asparaginyl) beta-hydroxylase, aspartyl-(asparaginyl)-b-hydroxylase, aspartyl-(asparaginyl)-beta-hydroxylase, aspartyl-(asparagyl)-beta-hydroxylase, aspartyl-asparaginyl-beta-hydroxylase, aspartylpeptide beta-dioxygenase, ASPH, EGF beta-hydroxylase, EGFH, factor inhibiting HIF, factor inhibiting hypoxia-inducible factor, factor inhibiting hypoxia-inducible transcription factor (HIF), factor-inhibiting hypoxia-inducible factor, FIH, HAAH, HIF asparaginyl hydroxylase, human aspartyl (asparaginyl) beta-hydroxylase, hypoxia-inducible factor asparaginyl hydroxylase |
| EC Number | 1.14.11.16 |
| CAS Registry Number | 122544-66-5 |
| Comments | Requires Fe2+. Some vitamin K-dependent coagulation factors, as well as synthetic peptides based on the structure of the first epidermal growth factor domain of human coagulation factor IX or X, can act as acceptors. |
| Cofactor | Fe2+ |
| History | |
| Reactions | Peptide L-aspartate + 2-oxoglutarate + O(2) = peptide 3-hydroxy-L- aspartate + succinate + CO(2). |
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