peptide-O-fucosyltransferase EC#: 2.4.1.221; ChemWhat Code: 1377522
Product Name | peptide-O-fucosyltransferase |
Example Structure | |
Synonyms | alpha-6-fucosyltransferase, core alpha6FucT, fucosyltransferase, guanosine diphosphofucose-glycoprotein, GDP-fucose glycoprotein fucosyltransferase, GDP-fucose protein O-fucosyltransferase, GDP-fucose:polypeptide fucosyltransferase, GDP-L-fucose-glycoprotein fucosyltransferase, GDP-L-fucose:polypeptide fucosyltransferase, glycoprotein fucosyltransferase, guanosine diphosphofucose-glycoprotein fucosyltransferase, N-acetyl-beta-D-glucosaminide alpha1–>6-fucosyltransferase, N-glycan alpha-6-fucosyltransferase, O-fucosyltransferase, O-fucosyltransferase 1, O-fucosyltransferase O-fut 1, O-fucT-1, O-fut1, OFUT1, OFUTI, Pofut1, POFUT2, protein O-fucosyltransferase 1, protein O-fucosyltransferase 2, protein O-fucosyltransferases 1, protein O-fucosyltransferases 2 |
EC Number | 2.4.1.221 |
CAS Registry Number | 9033/8/3 |
Comments | Involved in the biosynthesis of O-fucosylated epidermal growth factor (EGF) and thrombospondin type 1 repeats. The attachment of O-linked fucose to serine or threonine occurs on EGF domains within the sequence Cys-Xaa-Xaa-Gly-Gly-Ser/Thr-Cys. |
Cofactor | |
History | |
Reactions | Transfers an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine hydroxy group of a protein acceptor. |
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