Product Name
Peptidyl-dipeptidase Dcp
Example Structure
Synonyms
DCP, Dipeptidyl carboxypeptidase, dipeptidyl carboxypeptidase II, dipeptidylcarboxypeptidase, EC 3.4.15.1, EC 3.4.15.3, LdDCP, More
EC Number
3.4.15.5
CAS Registry Number
9015-82-1
Comments
Known from?E. coli?and?Salmonella typhimurium. A zinc metallopeptidase in peptidase family?M3?(thimet oligopeptidase family). Ac-Ala©àAla-Ala is a good test substrate [3]. Inhibited by captopril, as is peptidyl-dipeptidase A. Formerly EC?3.4.15.3, and included in EC?3.4.15.1.
Cofactor
Zn2+
History
Reactions
Hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1′ is Pro, or both P1 and P1′ are Gly.