peptidyltransferase EC#: 2.3.2.12; ChemWhat Code: 1377159
| Product Name | peptidyltransferase |
| Example Structure |  |
| Synonyms | L,D-transpeptidase, L,D-transpeptidase 2, LD-transpeptidase, LDT, LdtD, Ldtfm, LdtMt2, LdtMt5, peptidoglycan transpeptidase, peptidyl transferase, PT, PTase, PTC, ribosomal peptidyl transferase, ribosomal peptidyltransferase, ribosomal protein L27, transpeptidase |
| EC Number | 2.3.2.12 |
| CAS Registry Number | 9059-29-4 |
| Comments | The enzyme is a ribozyme. Two non-equivlant ribonucleoprotein subunits operate in non-concerted fashion in peptide elongation. The small subunit forms the mRNA-binding machinery and decoding center, the large subunit performs the main ribosomal catalytic function in the peptidyl-transferase center. |
| Cofactor | |
| History | |
| Reactions | Peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidyl(aminoacyl- tRNA(2)). |
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