| Product Name |
petromyzonol sulfotransferase |
| Example Structure |
 |
| Synonyms |
PZ-SULT |
| EC Number |
2.8.2.31 |
| CAS Registry Number |
|
| Comments |
The enzyme from the lamprey?Petromyzon marinus?can also use the corresponding 3-ketone as a substrate. It is stereoselective (5¦Á-cholane) and regioselective, exhibiting a preference for an hydroxy group at C-24. The enzyme is inactive when allocholic acid, which has a carboxy group at C-24, is used as a substrate. |
| Cofactor |
|
| History |
|
| Reactions |
3′-phosphoadenylyl sulfate + 5-alpha-cholan-3-alpha,7-alpha,12-alpha,24- tetrol = adenosine 3′,5′-bisphosphate + 5-alpha-cholan-3-alpha,7- alpha,12-alpha-triol 24-sulfate. |
