phenylacetyl-CoA dehydrogenase EC#: 1.17.5.1; ChemWhat Code: 1376011
Product Name | phenylacetyl-CoA dehydrogenase |
Example Structure | |
Synonyms | More, oxidase, phenylacetyl coenzyme A (alpha-oxidizing), phenylacetyl-CoA alpha-carbon-oxidizing oxidase, phenylacetyl-CoA-acceptor oxidoreductase, phenylacetyl-CoA:acceptor oxidoreductase |
EC Number | 1.17.5.1 |
CAS Registry Number | |
Comments | The enzyme from Thauera aromatica is a membrane-bound molybdenum¡ªiron¡ªsulfur protein. The enzyme is specific for phenylacetyl-CoA as substrate. Phenylacetate, acetyl-CoA, benzoyl-CoA, propanoyl-CoA, crotonyl-CoA, succinyl-CoA and 3-hydroxybenzoyl-CoA cannot act as substrates. The oxygen atom introduced into the product, phenylglyoxylyl-CoA, is derived from water and not molecular oxygen. Duroquinone, menaquinone and 2,6-dichlorophenolindophenol (DCPIP) can act as acceptor, but the likely physiological acceptor is ubiquinone [1]. A second enzyme, EC 3.1.2.25, phenylglyoxylyl-CoA hydrolase, converts the phenylglyoxylyl-CoA formed into phenylglyoxylate. |
Cofactor | iron-sulfur;Mo-molybdopterin |
History | |
Reactions | Phenylacetyl-CoA + H(2)O + 2 quinone = phenylglyoxylyl-CoA + 2 quinol. |
Buy Reagent | |
No reagent supplier? | Send quick inquiry to ChemWhat |
Want to be listed here as a reagent supplier? (Paid service) | Click here to contact ChemWhat |
Approved Manufacturers | |
Want to be listed as an approved manufacturer (Requires approvement)? | Please download and fill out this form and send back to approved-manufacturers@chemwhat.com |
Contact Us for Other Help | |
Contact us for other information or services | Click here to contact ChemWhat |