phorbol-diester hydrolase EC#: 3.1.1.51; ChemWhat Code: 1379253
| Product Name | phorbol-diester hydrolase |
| Example Structure |  |
| Synonyms | diacylphorbate 12-hydrolase, More, PDE74H, phorbol-12,13-diester 12-ester hydrolase |
| EC Number | 3.1.1.51 |
| CAS Registry Number | |
| Comments | Hydrolyses the 12-ester bond in a variety of 12,13-diacylphorbols (phorbol is a diterpenoid); this reaction inactivates the tumour promotor 12-O-tetradecanoylphorbol-13-acetate from croton oil. |
| Cofactor | |
| History | |
| Reactions | Phorbol 12,13-dibutanoate + H(2)O = phorbol 13-butanoate + butanoate. |
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