[phosphatase 2A protein]-leucine-carboxy methyltransferase EC#: 2.1.1.233; ChemWhat Code: 1376482

Product Name [phosphatase 2A protein]-leucine-carboxy methyltransferase
Example Structure Example Structure of [phosphatase 2A protein]-leucine-carboxy methyltransferase EC#: 2.1.1.233
Synonyms C-terminal leucine protein carboxyl methyltransferase-1, LCMT-1, LCMT1, leucine carboxy methyltransferase-1, leucine carboxyl methyltransferase, leucine carboxyl methyltransferase 1, leucine carboxyl methyltransferase-1, leucine carboxylmethyltransferase-1, leucine carboxymethyltransferase 1/phosphatase methylesterase 1, phosphatase 2A protein methyltransferase, PP2A LCMT, PP2A methyltransferase, PP2A-specific methyltransferase, PPM1, Ppm1p, PPMT, protein phosphatase 2A leucine carboxyl methyltransferase, protein phosphatase methyltransferase 1
EC Number 2.1.1.233
CAS Registry Number
Comments Methylates the C-terminal leucine of phosphatase 2A. A key regulator of protein phosphatase 2A. The methyl ester is hydrolysed by EC 3.1.1.89 (protein phosphatase methylesterase-1). Occurs mainly in the cytoplasm, Golgi region and late endosomes.
Cofactor
History
Reactions S-adenosyl-L-methionine + [phosphatase 2A protein]-leucine = S-adenosyl- L-homocysteine + [phosphatase 2A protein]-leucine methyl ester.

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